The expression and cellular localization of phospholipase D1 in the rodentretina

Authors
Lee, FJ Min, DS Kang, WS Lee, MY Oh, SJ Chun, MH
Citation
Fj. Lee et al., The expression and cellular localization of phospholipase D1 in the rodentretina, BRAIN RES, 905(1-2), 2001, pp. 240-244
Citations number
23
Categorie Soggetti
Neurosciences & Behavoir
Journal title
BRAIN RESEARCH
ISSN journal
00068993 → ACNP
Volume
905
Issue
1-2
Year of publication
2001
Pages
240 - 244
Database
ISI
SICI code
0006-8993(20010629)905:1-2<240:TEACLO>2.0.ZU;2-1
Abstract
Phospholipase D (PLD) is one of the intracellular signal transduction enzym es and plays an important role in a variety of cellular functions. We inves tigated the expression and cellular localization of the PLD isozyme PLD1 in the rodent retina. Western blot analysis showed the presence of PLD1 at th e protein level in the rat, mouse and guinea pig retinas. PLD1 immunoreacti vity was localized in all Muller cells. Thus, PLD1 protein appears to be im portant in the functions of these cells in the rodent retina. (C) 2001 Publ ished by Elsevier Science B.V.