Both the flashlamp-pumped dye laser and the long-pulsed tunable dye laser can improve results in port-wine stain therapy

Background At present, laser therapy of port-wine stains (PWS) using the fl ashlamp-pumped dye laser (FPDL) at 450 mus is accepted as the optimal appro ach. A few years ago, a new long-pulsed tunable dye laser (LPTDL, 1.5 ms) w as introduced for the treatment of leg veins. Objectives To investigate the efficacy and side-effects of FPDL vs. LPTDL t herapy of PWS. Methods Sixty-two patients with untreated PWS underwent test treatments wit h the FPDL (585 nm; 7-mm spot size; 5.75-7.0 J cm(-2) fluence) and LPTDL (5 85, 590, 595, 600 nm; 5-mm spot size; 11-20 J cm(-2) fluence). With the LPT DL, the epidermis was additionally cooled (Spray cooling device). The fadin g was evaluated clinically 6 weeks after the test treatments. Results Optimal fading was achieved by the LPTDL (greater than or equal to 585 nm) in 30 patients and by the FPDL in 12 patients. No difference was fo und in 20 patients. At 585 nm, the lasers worked equally well in 12 (FPDL) and 13 (LPTDL) patients, respectively. Results were independent of the loca lization of the PWS and of the patient's age. In spite of the longer pulse duration, the LPTDL treatment did not result in more side-effects as long a s sufficient cooling was provided. Conclusions The results provide evidence that wavelengths longer than 585 n m can increase the efficacy of treatment in some PWS. Owing to the reduced light absorption by haemoglobin at longer wavelengths and consequently incr eased depth of the vascular injury, larger vessels can be damaged more adeq uately using an increased fluence. The LPTDL at 585 nm seemed to be slightl y superior to the FPDL, while accepting that due to technical reasons the l aser parameters were not directly comparable. Availability of both lasers i ncreases the therapeutic possibilities in PWS.