Pemphigus foliaceus with prominent neutrophilic pustules

Authors
Matsuo, K Komai, A Ishii, K Futei, Y Amagai, M Deguchi, H Danno, K Hashimoto, T
Citation
K. Matsuo et al., Pemphigus foliaceus with prominent neutrophilic pustules, BR J DERM, 145(1), 2001, pp. 132-136
Citations number
21
Categorie Soggetti
Dermatology,"da verificare
Journal title
BRITISH JOURNAL OF DERMATOLOGY
ISSN journal
00070963 → ACNP
Volume
145
Issue
1
Year of publication
2001
Pages
132 - 136
Database
ISI
SICI code
0007-0963(200107)145:1<132:PFWPNP>2.0.ZU;2-V
Abstract
We describe four patients with generalized scaly and pustular skin lesions showing extensive neutrophilic infiltration in the subcorneal region of the epidermis. Immunofluorescence, immunoblot and enzyme-linked immunosorbent assay analyses detected IgG antibodies reacting exclusively with desmoglein 1, the pemphigus foliaceus antigen. This study indicates that pemphigus fo liaceus may show prominent neutrophilic pustular skin lesions.