The Casimir stress on a spherical shell in the de Sitter background for a m
assless scalar field satisfying Dirichlet boundary conditions on the shell
is calculated. The metric is written in conformally flat form. Although the
metric is time dependent, no particles are created. The Casimir stress is
calculated for inside and outside of the shell with different backgrounds c
orresponding to different cosmological constants. The detailed dynamics of
the bubble depends on different parameters of the model. Specifically, bubb
les with a true vacuum inside expand if the difference in the Vacuum energi
es is small, otherwise they collapse.