Clinical features at presentation of anterior segment pigment dispersion syndrome

One hundred and twenty patients with anterior segment pigment dispersion sy ndrome were reviewed in order to ascertain the features of the condition an d form some idea of their significance. Patients were regarded as having pi gment dispersion syndrome on the basis of heavy trabecular mesh pigmentatio n with at least one other feature of the condition. Although common in men, 44 patients, or a little over one-third, were women. Average age at presen tation was 47.8 years with women presenting 10 years later than men. Intrao cular pressure was very variable at presentation being less than 20 mmHg in 23 patients. Some patients with elevated pressure had no field loss. Varia ble myopia was recorded in 38 patients; 30 patients were not myopic. Anteri or chamber depth was also variable, the average being 3.0 mm, but six patie nts had a depth of 2.2 mm or less. The syndrome is extremely variable in it s features at presentation. The mild hypoplasia and the hypoperfusion of th e iris previously described is consistent with the laxity of the iris noted by Ritch and colleagues.