Analytical application of oligopyrrole macrocycles

Progress of modern analytical chemistry is closely related with advancement in other fields such as organic chemistry and biochemistry. Successful sol ution of current scientific problems is inconceivable without close coopera tion of different chemical disciplines. As an example of such hot and very intricate theme research in the field of molecular recognition of biologica lly active compounds can serve, where numerous methods of analytical chemis try, organic chemistry and biochemistry can suitably be utilized, elaborate d and brought into consonance. This multidisciplinary overlap logically lea ds to the advent of new scientific fields with their own tools, methodologi es and subjects of exploration - bioanalytical chemistry and nanotechnology . This review covers different aspects of analytical application of oligopy rrole macrocycles (mainly porphyrins and sapphyrins). These compounds are w idely used in analytical chemistry due to their outstanding optical propert ies. In our contribution oligopyrrole macrocycles are considered as signali ng and structural parts of chemical receptors and selectors in various appl ications. Introduction of different moieties into meso-position of macrocyc lic rings allows to obtain e.g., sterically well-organized receptors for re cognition of biologically important analytes, new chromatographic materials , and powerful tools in electrochemical research. Finally, future trends in the field are outlined briefly.