Citation
B. Lustig et Kt. Jeang, Biological applications of hammerhead ribozymes as anti-viral molecules, CURR MED CH, 8(10), 2001, pp. 1181-1187
Citations number
65
Categorie Soggetti
Pharmacology & Toxicology
Journal title
CURRENT MEDICINAL CHEMISTRY
ISSN journal
09298673
→ ACNP
Volume
8
Issue
10
Year of publication
2001
Pages
1181 - 1187
Database
ISI
SICI code
0929-8673(200108)8:10<1181:BAOHRA>2.0.ZU;2-W
Abstract
Ribozymes are catalytic RNAs that can cleave substrate RNAs in a sequence s
pecific manner. Here we survey, in brief, the structure of hammerhead and h
airpin ribozymes and discuss their applications as molecular antiviral mole
cules for HIV-1.