The results are discussed of a systematic investigation into the electromag
netic held (EMP) exposure consequences on human lymphocytes. These artifici
al fields have intensities comparable to the Earth's magnetic field, and ar
e used for exposures up to 4 days. Different and complementary techniques a
re used to safely assess the consequences of EMFs on the cells; in particul
ar, morphology, metabolism, and population dynamics are investigated. The r
ecourse to ultramicroscopy, pressure monitoring in sealed bottles, atomic m
ass spectroscopy, and cytofluorimetry techniques give good insight into the
EMF-induced changes. A statistically significant deviation of irradiated s
amples with respect to control samples is reported. A critical analysis and
a survey of similar experiments reported in the literature led us to exami
ne the experimental setup with attention to the geometry of the irradiation
system. Yeast cells were used as a model system to statistically test the
different steps in the overall procedure, thanks to information gathered du
ring a radiobiology experiment performed at the Rutherford Appleton Laborat
ory. Finally, the role of different magnetic field detectors in the reprodu
cibility of the experiments is carefully discussed.