Enantioselective fate of chiral chlorinated hydrocarbons and their metabolites in environmental samples

Gas chromatographic enantioseparation of chiral organochlorines (alpha -HCH , cis- and trans-chlordane, heptachlor, heptachlor epoxide, oxychlordane, o ,p'-DDT, compounds of technical toxaphene, stable atropisomeric PCBs and me thylsulfonyl-PCBs) has been achieved during the last decade. For this purpo se chiral stationary phases based on cyclodextrin derivatives have been app lied in combination with GC/ECD, GC/MS, MDGC, and MS/MS. With these techniq ues methods have been developed which have been used to study the enantiose lective fate of the chiral organochlorines. Changes in the enantioratios an d conclusions drawn are reviewed.