K. Mogilaiah et Pr. Reddy, Hypervalent-iodine mediated solid state synthesis of 1,8-naphthyridinyl-1,3,4-oxadiazoles, I J CHEM B, 40(7), 2001, pp. 619-621
Citations number
12
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY
2-Trifluoromethyl-1,8-naphthyridine-3-carboxylic acid arylidene-hydrazides
(acylhydrazones) 2 can be conveniently converted to the corresponding 5-ary
l-2-(2-trifluoromethyl-1,8-naphthyridin-3-yl)- 1,3,4-oxadiazoles 3 with iod
obenzene diacetate (IBD) under solid state conditions. The reaction proceed
s efficiently giving the products in excellent yields at ambient temperatur
e.