The cycle time-throughput curve is one of the most important analytical too
ls used to assess operating policies in manufacturing systems. Unfortunatel
y, the generation of this curve is complicated and time consuming when gene
ration is based upon extensive simulation analysis. This paper presents a s
imulation-based, fixed sample size strategy for generating a cycle time-thr
oughput curve with minimal mean square error that mitigates the typical pro
blems associated with a simulation-based cycle time-throughput curve. The s
trategy comprises two components, the sampling method and sampling weights.
A queuing network of five workstations in series is used for validation of
the approach. Results indicate that the sampling method using antithetic v
ariates is effective in reducing the variance as well as bias of a cycle ti
me-throughput curve. Furthermore, this method is robust to the sample size.
Given a sufficiently large sample, the combination of common random number
s and antithetic variates is preferred. A reduction in the sample size and
complexity of the system increases the significance of the sampling weights
.