Yy. Hsieh et al., Antral follicle counting in predicting the retrieved oocyte number after ovarian hyperstimulation, J AS REPROD, 18(6), 2001, pp. 320-324
Purpose: To evaluate the antral follicle (AF) counting in predicting the ou
tcome after controlled ovarian hyperstimulation (COH) and IVF-ET:
Methods: Infertile women who accepted the COH and IVF-ET were included pros
pectively Day-3 AF number was determined by transvaginal sonography. They w
ere divided into three groups: Group 1: less than or equal to3 AF; Group 2:
4-10 AF; Group 3: greater than or equal to 11 AF. Retrieval oocyte number,
embryo number, pregnancy rate (PR), and implantation rate (IR) of the thre
e groups were compared.
Results: A total of 372 cycles were included. Patients in Groups 1, 2, and
3 were statistically different in age (35.3 vs. 31.9 vs. 28.5), Day-3 FSH (
14.3 vs. 5.9 vs. 4.1), cancellation (34.4% vs. 2.7% vs. 0.9%), gonadotropin
dosage, retrieval oocyte number (2.9 vs. 8.2 vs. 14.5), embryo number (2.2
vs 6.5 vs. 11.7), PR (11.1% vs. 34.6% vs 35.0%, and IR (3.0% vs. 8.2% vs.
8.9%).
Conclusions: Patients with less than or equal to3 AF have a significantly h
igher cancellation rate, fewer retrieved oocyte number, and lower PR. Combi
nation of AF counting and basal FSH level increased the sensitivity in pred
icting the ovarian reserve. Retrieved oocyte number could be predicted by t
he formula: oocyte = 0.802 x AF + 2.01.