The sources of ligninocellulose that occur in various forms in nature are s
o vast that they can only be compared to those of water. The results of sev
eral, mon recent experiments showed that laccase probably possesses the big
ability for "lignin-barrier" breakdown of ligninocellulose. The degradatio
n of this compound is currently understood as an enzymatic process mediated
by small molecules, therefore, this review will focus on the role of these
mediators and radicals working in concert with enzymes. The fungi having a
versatile machinery of enzymes are able to attack directly the "lignin-bar
rier" or can use a multienzyme system including "feed-back" type enzymes al
lowing for simultaneons transformation of lignin and carbohydrate compounds
.