Cytochrome P450 database

This paper describes a specialized database dedicated exclusively to the cy tochrome P450 superfamily. The system provides the impression of superfamil y's nomenclature and describes structure and function of different P450 enz ymes. Information on P450-catalyzed reactions, substrate preferences, pecul iarities of induction and inhibition is available through the database mana gement system. Also the source genes and appropriate translated proteins ca n be retrieved together with corresponding literature references. Developed programming solution provides the flexible interface for browsing , searching, grouping and reporting the information. Local version of datab ase manager and required data files are distributed on a compact disk. Besi des, there is a network version of the software available on Internet. The network version implies the original mechanism, which is useful for the per manent online extension of the data scope.