A new one-pot synthesis of 2-quaternary 1,3-diketones

Authors
Ren, SK Wang, F Dou, HN Fan, CA He, L Song, ZL Xia, WJ Li, DR Jia, YX Li, X Tu, YQ
Citation
Sk. Ren et al., A new one-pot synthesis of 2-quaternary 1,3-diketones, SYNTHESIS-S, (16), 2001, pp. 2384-2388
Citations number
19
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
16
Year of publication
2001
Pages
2384 - 2388
Database
ISI
SICI code
0039-7881(200112):16<2384:ANOSO2>2.0.ZU;2-R
Abstract
A facile one-pot synthesis of 1,3-diketones with stereogenic quaternary cen ter at C-2 has been developed on the basis of an oxidative-rearrangement of a series of tertiary a-hydroxy epoxides on treatment with pyridinium chlor ochromate (PCC). A possible mechanism is also discussed.