Synthesis of pinacol arylboronates via cross-coupling reaction of bis(pinacolato)diboron with chloroarenes catalyzed by palladium(0)-tricyclohexylphosphine complexes

Authors
Ishiyama, T Ishida, K Miyaura, N
Citation
T. Ishiyama et al., Synthesis of pinacol arylboronates via cross-coupling reaction of bis(pinacolato)diboron with chloroarenes catalyzed by palladium(0)-tricyclohexylphosphine complexes, TETRAHEDRON, 57(49), 2001, pp. 9813-9816
Citations number
47
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
57
Issue
49
Year of publication
2001
Pages
9813 - 9816
Database
ISI
SICI code
0040-4020(200112)57:49<9813:SOPAVC>2.0.ZU;2-9
Abstract
The cross-coupling reaction of bis-(pinacolato)diboron with chloroarenes to yield pinacol arylboronates was carried out in 1,4-dioxane at 80 degreesC in the presence of KOAc (1.5 equiv.) and Pd(dba)(2)/2.4PCy(3) (3-6 mol%). T he catalyst was also effective to carry out analogous coupling with aryl br omides or triflates under milder conditions than those of the previous proc edures catalyzed by PdCl2(dppf) in DMSO. (C) 2001 Elsevier Science Ltd. All rights reserved.