Stereocontrolled approaches to 2-(2-aminoalkyl)-1-hydroxycyclopropanes

Authors
Baird, MS Huber, FAM Clegg, W
Citation
Ms. Baird et al., Stereocontrolled approaches to 2-(2-aminoalkyl)-1-hydroxycyclopropanes, TETRAHEDRON, 57(49), 2001, pp. 9849-9858
Citations number
21
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
57
Issue
49
Year of publication
2001
Pages
9849 - 9858
Database
ISI
SICI code
0040-4020(200112)57:49<9849:SAT2>2.0.ZU;2-C
Abstract
(1S,2S)-2[(S)-Amino(4-methoxyphenyl)methyl]cyclopropan-1-of together with a range of racemic 2-(2-aminoalkyl)-1-hydroxy-cyclopropanes were prepared by a stepwise procedure involving a 1,3-dipolar cycloaddition of a nitrile ox ide to a cyclopropene followed by reduction of the derived bicycle. (C) 200 1 Elsevier Science Ltd. All rights reserved.