Stereocontrolled synthesis of contignasterol's side chain

Authors
Izzo, I Pironti, V Della Monica, C Sodano, G De Riccardis, F
Citation
I. Izzo et al., Stereocontrolled synthesis of contignasterol's side chain, TETRAHEDR L, 42(51), 2001, pp. 8977-8980
Citations number
18
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
51
Year of publication
2001
Pages
8977 - 8980
Database
ISI
SICI code
0040-4039(200112)42:51<8977:SSOCSC>2.0.ZU;2-V
Abstract
The four models of the contignasterol's side chains (2-5) have been stereos pecifically prepared. The key reaction in the synthesis is a dimethylalumin um chloride-mediated 'ene' reaction between the steroid derivative 6 and th e pseudo-enantiomeric aldehydes 7 and 8. (C) 2001 Elsevier Science Ltd. All rights reserved.