Synthesis of ethyl 3-cyano-2-methylcinnamates and 3-cyano-2-methylcinnamonitriles from the Baylis-Hillman acetates

Authors
Chung, YM Gong, JH Kim, TH Kim, JN
Citation
Ym. Chung et al., Synthesis of ethyl 3-cyano-2-methylcinnamates and 3-cyano-2-methylcinnamonitriles from the Baylis-Hillman acetates, TETRAHEDR L, 42(51), 2001, pp. 9023-9026
Citations number
23
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
51
Year of publication
2001
Pages
9023 - 9026
Database
ISI
SICI code
0040-4039(200112)42:51<9023:SOE3A3>2.0.ZU;2-2
Abstract
The reaction of the DABCO salts 2, generated in situ from the Baylis-Hillma n acetates 1, and KCN in aqueous THF gave ethyl 3-cyano-2-methylcinnamates 4a-d and 3-cyano-2-methylcinnamonitriles 4e-f in good yields. (C) 2001 Else vier Science Ltd. All rights reserved.