As the commercial production of transgenic annual crops becomes a reality i
n many parts of the world, many people wonder if the genetic engineering of
perennial trees will allow their eventual commercialization. Not long ago,
trees were considered to be recalcitrant material for most molecular biolo
gy techniques, including genetic transformation. However, transgenes for sh
ortening the juvenile phase or for phytoremediation purposes have now been
incorporated, and the alteration of lignin biosynthesis and increased cellu
lose accumulation in forest trees have also been accomplished. For long-liv
ed tree species, new questions arise regarding the stability of integration
and expression of foreign genes. Biosafety considerations, including trans
gene dispersion through the pollen and advances in strategies to avoid this
, are also important.