Anaerobic wastewater treatment (AnWT) is considered as the most cost-effect
ive solution for organically polluted industrial waste streams. Particularl
y the development of high-rate systems, in which hydraulic retention times
are uncoupled from solids retention times, has led to a world-wide acceptan
ce of AnWT. In the last decade up to the present, the application potential
s of AnWT are further explored. Research shows the feasibility of anaerobic
reactors under extreme conditions, such as low and high temperatures. Also
toxic and/or recalcitrant wastewaters, that were previously believed not t
o be suitable for anaerobic processes, are now effectively treated. The rec
ent advances are made possible by adapting the conventional anaerobic high-
rate concept to the more extreme conditions. Staged anaerobic reactor conce
pts show advantages under non-optimal temperature conditions as well as dur
ing the treatment of chemical wastewater. In other situations, a staged ana
erobic - aerobic approach is required for biodegradation of specific pollut
ants, e.g. the removal of dyes from textile processing wastewaters. The cur
rent paper illustrates the benefits of reactor staging and the yet un-explo
ited potentials of high-rate AnWT.