Many papers have addressed the technical aspects of free tissue transf
er in head and neck cancer patients. However, there has not been a cri
tical assessment of the impact of free tissue transfer on resource uti
lization and patient morbidity compared with pedicle flap reconstructi
ons. Two cohorts of patients derived from 245 consecutive reconstructi
ons were tightly matched by age, site, stage, and histology, yielding
44 patient pairs differing in method of reconstruction. Patients under
going free flap reconstruction spent more time in the operating room t
han those reconstructed with pedicled flaps (993 min vs. 777 min, P <
0.0001). The group with free flap reconstruction spent fewer days in t
he surgical intensive care unit and hospital (2 days vs. 2.5 days; 18.
5 days vs. 22.6 days). This difference is attributed to the paucity of
postoperative complications in the group with free flap reconstructio
n (fistula formation 4.5% vs. 21%, P < 0.04). These data indicate that
the continued use of sophisticated reconstructive techniques in head
and neck cancer patients is economically sound as assessed by patient
morbidity and resource utilization.