We measured the maximum aggregation rate (MAR) of platelets in 770 pat
ients with malignant head and neck tumors, 55 patients with benign tum
ors of the head and neck, and 164 healthy people as a control group. T
he results were as follows: 1. the mean MAR value of patients with mal
ignant tumors was significantly higher than the control group mean val
ue; 2. prior to treatment, the mean MAR value increased with advancing
tumor stage; 3. both MAR values of relapsed or metastasized patients
and of nonsurvivors in stage III and IV increased significantly compar
ed with survivors or patients recovering from malignant tumors. The re
sults of the present study suggest that MAR values of patients with ma
lignant tumors of the head and neck may serve as indicators in evaluat
ing therapeutic procedures and prognosis.