The operating principles of Laser Doppler Perfusion Imaging (LDPI) for
visualization of the tissue blood perfusion are explained. Using this
emerging technology skin perfusion has been investigated in healthy v
olunteers and in patients with various conditions that affect skin blo
od flow. LDPI is anticipated to be particularly useful in evaluation o
f peripheral circulation in diabetics, as an objective tool in irritan
cy patch testing, assessment of burnt skin and visualization of spot-w
ise hyperperfusion in breast skin in association with carcinoma.