Introduction The ultrasonographic appearance of mycetoma is described
in this prospective study. Methods One hundred patients with foot swel
lings had sonographic evaluation of the swelling and surgical excision
within 2 weeks of ultrasonography. The histopathological findings wer
e compared with the preoperative images. Some of the excised swellings
and grains were also imaged and compared with the in vivo findings. R
esults The mycetoma grains, their capsules and the accompanying inflam
matory granulomas have characteristic ultrasonographic appearances. In
eumycetoma lesions, the grains produce numerous, sharp hyper-reflecti
ve echoes and there are single or multiple thick-walled cavities with
no acoustic enhancement. In actinomycetoma, the findings are similar b
ut the hyper-reflective echoes are fine, closely aggregated and common
ly settle at the bottom of the cavities. None of the non-mycetoma foot
swellings (which included lipoma, ganglion, foreign body granuloma an
d others) studied had these features. Conclusion Ultrasonography is si
mple, non-invasive, quick, reproducible and acceptable to patients. My
cetoma has characteristic ultrasonographic features. Furthermore, ultr
asonography delineates the extent of mycetoma more accurately than cli
nical examination alone.