POSTTRANSPLANTATION LYMPHOPROLIFERATIVE DISORDER IN A RENAL-ALLOGRAFTRECIPIENT

Citation
S. Goral et al., POSTTRANSPLANTATION LYMPHOPROLIFERATIVE DISORDER IN A RENAL-ALLOGRAFTRECIPIENT, American journal of kidney diseases, 30(2), 1997, pp. 301-307
Citations number
18
Categorie Soggetti
Urology & Nephrology
ISSN journal
02726386
Volume
30
Issue
2
Year of publication
1997
Pages
301 - 307
Database
ISI
SICI code
0272-6386(1997)30:2<301:PLDIAR>2.0.ZU;2-9
Abstract
As a complication of immunosuppressive therapy, solid organ and bone m arrow transplant recipients have an increased risk of developing post transplant lymphoproliferative disorder (PTLD). Epstein-Barr virus (EB V) infection and the degree of immunosuppression have been identified as risk factors for the development of this complication, The clinical presentation includes a spectrum of disorders ranging from a benign i nfectious mononucleosis-like syndrome with fever and cervical adenopat hy to multiorgan failure leading to death, Although, T-cell lesions ha ve been described, PTLD is usually associated with a polyclonal or mon oclonal B-cell proliferation, In this report, we present a renal trans plant recipient with a perirenal mass diagnosed as PTLD. (C) 1997 by t he National Kidney Foundation, Inc.