A CYCLODEXTRIN TO REVERSE THE REGIOSELECTIVITY OF NITRILE OXIDE CYCLOADDITION TO A TERMINAL ALKENE

Authors
MEYER AG EASTON CJ LINCOLN SF SIMPSON GW
Citation
Ag. Meyer et al., A CYCLODEXTRIN TO REVERSE THE REGIOSELECTIVITY OF NITRILE OXIDE CYCLOADDITION TO A TERMINAL ALKENE, Chemical communications, (16), 1997, pp. 1517-1518
Citations number
18
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
16
Year of publication
1997
Pages
1517 - 1518
Database
ISI
SICI code
1359-7345(1997):16<1517:ACTRTR>2.0.ZU;2-Q
Abstract
The 1,3-dipolar cycloaddition of 4-tert-butylbenzonitrile oxide with 6 (A)-acrylamido-6(A)-deoxy-beta-cyclodextrin in aqueous solution favour s formation of the 4-substituted isoxazoline, in contrast to the norma l predominance of the 5-substituted regioisomer from reactions of mono substituted alkenes.