ANTIFUNGAL PATENTS APPEARING FROM JUNE 1995 TO JUNE 1997

Claims related to the discovery of new antifungal agents and methods t o improve existing marketed drugs dominate the patent literature datin g from June 1995 to June 1997. The bulk of this review deals with entr ies that involve the synthesis and evaluation of new compounds and nov el analogues of known classes of antifungals. Coverage related to the development of combination therapies and the use of formulation vehicl es to improve the physicochemical properties, pharmacokinetics and tox icity profiles associated with parent compounds is also included.