CHIRAL THIOIMIDAZOLINE LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC ALLYLATION

Authors
MORIMOTO T TACHIBANA K ACHIWA K
Citation
T. Morimoto et al., CHIRAL THIOIMIDAZOLINE LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC ALLYLATION, Synlett, (7), 1997, pp. 783
Citations number
28
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
7
Year of publication
1997
Database
ISI
SICI code
0936-5214(1997):7<783:CTLFPA>2.0.ZU;2-7
Abstract
Chiral thioarylimidazolines 1,2 were prepared as a new class of SN-hyb rid ligands. Asymmetric allylic substitution of 1,3-diphenyl-2-propeny l pivalate 11 with dimethyl malonate in the presence of BSA-LiOAc has been successfully carried out with a chiral catalyst of a thioimidazol ine l-palladium complex in high enantioselectivities of up to 96% ee.