TOWARDS A SYNTHESIS OF EPOTHILONE-A - RAPID ASSEMBLY OF THE C1-C6 ANDC7-C12 FRAGMENTS

Authors
DEBRABANDER J ROSSET S BERNARDINELLI G
Citation
J. Debrabander et al., TOWARDS A SYNTHESIS OF EPOTHILONE-A - RAPID ASSEMBLY OF THE C1-C6 ANDC7-C12 FRAGMENTS, Synlett, (7), 1997, pp. 824
Citations number
25
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
7
Year of publication
1997
Database
ISI
SICI code
0936-5214(1997):7<824:TASOE->2.0.ZU;2-#
Abstract
A very short 4-step synthesis of the C1-C6 and C7-C12 fragments 3 and 4 of epothilone A (la), starting from bornane-10,2-sultam 5, was achie ved in 77% and 56% overall yield respectively.