NEAR-INFRARED REFLECTANCE SPECTROMETRY IN THE STUDY OF ATOPY .2. INTERACTIONS BETWEEN THE SKIN AND POLYETHYLENE-GLYCOL-400, ISOPROPYL MYRISTATE AND HYDROGEL

Authors
DREASSI E CERAMELLI G MURA P PERRUCCIO PL VOCIONI F BARTALINI P CORTI P
Citation
E. Dreassi et al., NEAR-INFRARED REFLECTANCE SPECTROMETRY IN THE STUDY OF ATOPY .2. INTERACTIONS BETWEEN THE SKIN AND POLYETHYLENE-GLYCOL-400, ISOPROPYL MYRISTATE AND HYDROGEL, Analyst, 122(8), 1997, pp. 771-776
Citations number
17
Categorie Soggetti
Chemistry Analytical
Journal title
Analyst → ACNP
ISSN journal
00032654
Volume
122
Issue
8
Year of publication
1997
Pages
771 - 776
Database
ISI
SICI code
0003-2654(1997)122:8<771:NRSITS>2.0.ZU;2-6
Abstract
An investigation into the existence of spectral differences and differ ences in response in terms of water and lipid content between normal a nd atopic skin after interaction with chemical agents is described, Th ree compounds were taken as models: a prevalently hydrophilic solvent (polyethylene glycol, PEG 400), a prevalently lipophilic solvent (isop ropyl myristate) and a hydrophilic pharmaceutical (gel) used to promot e contact in electrocardiography, Using principal component analysis i t was possible to distinguish atopic and normal subjects by simple con tact of the skin with chemical agents.