SYNTHESIS, NMR SPECTROSCOPIC AND X-RAY CRYSTALLOGRAPHIC STUDIES OF N-ACETYL-3-BUTANOYLTETRAMIC ACID

Authors
BARKLEY JV MARKOPOULOS J MARKOPOULOU O
Citation
Jv. Barkley et al., SYNTHESIS, NMR SPECTROSCOPIC AND X-RAY CRYSTALLOGRAPHIC STUDIES OF N-ACETYL-3-BUTANOYLTETRAMIC ACID, Perkin transactions. 2, (6), 1994, pp. 1271-1274
Citations number
34
Categorie Soggetti
Chemistry Physical","Chemistry Inorganic & Nuclear
Journal title
Perkin transactions. 2 → ACNP
ISSN journal
03009580
Issue
6
Year of publication
1994
Pages
1271 - 1274
Database
ISI
SICI code
0300-9580(1994):6<1271:SNSAXC>2.0.ZU;2-C
Abstract
The reaction of N-acetylglycine p-nitrophenyl ester with the anion of an active methylene compound proceeds to give N-acetyl-3-butanoyltetra mic acid. The influence of the N-acetyl group on the equilibrium betwe en different 'internal' and 'external' tautomeric forms of N-acetyl-3- butanoyltetramic acid was investigated by H-1 and C-13 NMR spectroscop y. The structure of this compound was confirmed by an X-ray crystal st ructure determination.