FULLY AUTOMATED QUANTITATIVE-ANALYSIS OF DNA IN SOLID TUMORS

An automatic machine, dedicated to solid tumor DNA ploidy quantitation has been built in order to provide pathologists with a tool usable in clinical practice. Main efforts were focused an an automation of each step of the analysis and on an elimination of any subjective choice, while preserving the quality of measurement. As the software is indepe ndent of the machine architecture, it offers performances which increa se in parallel with the rapid evolution of the computers. An illustrat ion of the various functionalities of the automaton is proposed throug h the study of deparaffined breast cancer samples.