Autologous transplantation in brachial plexus injuries has become sign
ificantly more efficacious through increased knowledge of the microtop
ographic anatomy of the fascicle structures and the refinement of micr
o-neurosurgical techniques. Recovery of shoulder and upper arm functio
ns can be achieved with autologous transplantation in the majority of
patients under optimized conditions. However, attempts to restore fore
arm, hand and finger functions in this way have been disappointing so
far. Therapeutic success is primarily governed by early decision makin
g, selection of adequate surgical strategies and intensive and longlas
ting postoperative management.