Objective: To evaluate the results of axillofemoral bypass grafting us
ing externally supported polytetrafluoroethylene. Design: Consecutive
patients who were operated on by us from 1983 to the present were pros
pectively followed up in a vascular registry. The results of surgery w
ith respect to morbidity and mortality, patency, limb salvage, and pat
ient survival were determined by life-table methods. Patients: A stand
ardized operative technique was used to perform 184 axillofemoral bypa
ss procedures in 164 consecutive patients (age range, 14 to 90 years;
mean age, 67 years; female, 33%). Follow-up ranged from 0 to 95 months
(mean, 23 months). Results: Ischemia was the indication for 83% of th
e procedures, and aortic sepsis was the indication for 16%. There were
nine operative deaths (5%) and 17 major complications. Life-table pri
mary patency, limb salvage, and survival rates at 5 years were 71%, 92
%, and 52%, respectively. Indication for surgery, patency of the super
ficial femoral artery, and the performance of multilevel procedures di
d not significantly influence patency. Conclusions: The results of axi
llofemoral grafting using polytetrafluoroethylene are equivalent to th
ose achieved with other accepted methods of treatment for lower extrem
ity ischemia, including balloon angioplasty, aortofemoral bypass, and
infrainguinal bypass. Axillofemoral bypass is an appropriate technique
that is deserving of more widespread use.