EFFECTIVENESS OF GARLIC ON THE RADICAL ACTIVITY IN RADICAL GENERATINGSYSTEMS

Citation
B. Torok et al., EFFECTIVENESS OF GARLIC ON THE RADICAL ACTIVITY IN RADICAL GENERATINGSYSTEMS, Arzneimittel-Forschung, 44-1(5), 1994, pp. 608-611
Citations number
16
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
ISSN journal
00044172
Volume
44-1
Issue
5
Year of publication
1994
Pages
608 - 611
Database
ISI
SICI code
0004-4172(1994)44-1:5<608:EOGOTR>2.0.ZU;2-L
Abstract
The radical scavenging capacity of garlic (allium sativum) has been in vestigated in vitro in radical generating systems by electron paramagn etic resonance (EPR) and low-level chemiluminescence measurements. Gar lic (both the homogenate of 10% in physiological saline solution and i ts supernatant) was able to reduce the radicals generated by the Fento n reaction and trapped by phenyl-butyl-nitron for EPR measurements. Al so radicals present in cigarette smoke could be reduced by garlic as j udged from chemiluminescence in the presence of tert.-butyl-hydroperox ide. According to the in vitro measurements garlic contains substances which have significant radical scavenging capacity.