INFECTIOUS PARTICLES DERIVED FROM SEMLIKI-FOREST-VIRUS VECTORS ENCODING MURINE LEUKEMIA-VIRUS ENVELOPES

Authors
LEBEDEVA I FUJITA K NIHRANE A SILVER J
Citation
I. Lebedeva et al., INFECTIOUS PARTICLES DERIVED FROM SEMLIKI-FOREST-VIRUS VECTORS ENCODING MURINE LEUKEMIA-VIRUS ENVELOPES, Journal of virology, 71(9), 1997, pp. 7061-7067
Citations number
27
Categorie Soggetti
Virology
Journal title
Journal of virology → ACNP
ISSN journal
0022538X
Volume
71
Issue
9
Year of publication
1997
Pages
7061 - 7067
Database
ISI
SICI code
0022-538X(1997)71:9<7061:IPDFSV>2.0.ZU;2-K
Abstract
Semliki Forest virus vectors encoding murine leukemia virus (MLV) enve lope protein with a truncated cytoplasmic tail generate submicrometer, cell-associated, membranous particles that transmit replication compe tent vector RNA specifically to cells bearing the MLV receptor. Such ' 'minimal'' viruses could have applications as retroviral vaccines or i n the study of virus evolution.