GENDER AND ALCOHOL DOSING - A PROCEDURE FOR PRODUCING COMPARABLE BREATH ALCOHOL CURVES FOR MEN AND WOMEN

Gender differences in peak breath alcohol concentrations (BrACs) reach ed in alcohol administration studies can make the interpretation of st udy findings difficult. This study evaluated the CBAC computer program as a way of mimimizing gender differences in the BrAC curve. After co nsuming a predrink meal that was adjusted by body mass, 31 female end 27 male subjects consumed an alcoholic beverage targeted for either 0. 04% or 0.08%. Mean peak BrACs for women and men were not significantly different. Similarly, the four BrAC readings obtained over the first 2 hr postdrink showed no gender differences, A dose x gender interacti on was observed on time to peak BrAC, with women reaching peak BrAC fa ster than men only in the high dose groups. By decreasing gender diffe rences in BrAC curves, this dosing procedure can aid in reducing the p otential confound of dose and gender.