A CASE OF BEDNAR TUMOR - IMMUNOHISTOCHEMICAL POSITIVITY FOR CD34

Citation
T. Kobayashi et al., A CASE OF BEDNAR TUMOR - IMMUNOHISTOCHEMICAL POSITIVITY FOR CD34, Dermatology, 195(1), 1997, pp. 57-59
Citations number
19
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
ISSN journal
10188665
Volume
195
Issue
1
Year of publication
1997
Pages
57 - 59
Database
ISI
SICI code
1018-8665(1997)195:1<57:ACOBT->2.0.ZU;2-2
Abstract
A 42-year-old Japanese man with a Bednar tumor is described. The skin showed a slightly elevated, red, partially dark blue, dermal nodule gr owing into the deep subcutaneous tissue. The histological specimen sho wed two types of tumor cells, spindle-formed cells with no melanin gra nules and melanin-laden cells. Immunohistochemical stainings for CD34 and S-100 protein revealed that the former cells showed positivity onl y for CD34, while the latter were only pos itive for S-100 protein. Th ese results suggest that the Bednar tumor is a dermatofibrosarcoma pro tuberans in which melanin-laden cells coexist.