Thrombosis and pulmonary embolism associated with air travelling is kn
own as <<economy class syndrome>>. However, as it is observed even usi
ng other means of transportation, it can generally be described as <<t
raveller's thrombosis>>. Our own observations include 5 patients with
thrombo-embolic disease, which occurred after long-distance travel. In
respect to the large number of travellers, the reported incidence of
associated thrombosis seems to be remarkably low, and there is no epid
emilogical evidence about travel and thromboembolic disease. On the ot
her hand, retrospective analysis of patients with manifest thrombosis
of any origin reveals in about 5% the circumstances of transportation
as possible agent. Anyhow, according to literature the risk of thrombo
sis could be regarded as quite low. Preventive action during long-dist
ance travelling should be taken into considerations in patients with h
igh risk of thromboembolism.