Purpose: To evaluate normal retrograde cholangiograms to determine a n
ormal range of ductal calibers and identify its variation with age. Ma
terials and methods: The retrograde cholangiograms of 136 patients (ag
e range: 17-84 years; mean age 49.8 years +/- 17.3 [standard deviation
]) with clinical followup and subsequent studies suggesting normal bil
iary trees were evaluated, Patients with previous cholecystectomy, cho
ledocholithiasis, or pancreatitis were excluded. Common bile duct (CBD
) and common hepatic duct (CHD) sizes were measured. Results: Measurem
ents uncorrected for radiographic magnification of CBD revealed a mean
of 8.5 mm +/- 2.7 mm [standard deviation] and CHD had a mean of 8.1 m
m +/- 2.6 mm. There was an increase in CBD caliber by 0.5 mm per decad
e of increasing age (p < 0.001) and an increase in CHD caliber by 0.35
mm per decade of age (p < 0.01). Conclusion: The range of normal chol
angiographic bile duct caliber is wide and a CBD caliber of 13.9 mm oc
curs at the top of this range (mean plus two standard deviations), The
re is a small but statistically significant trend of ductal dilatation
with advancing age.