REGIOSELECTIVE LIPASE-CATALYZED SYNTHESIS OF DIESTER CROWNS - NEW ASYMMETRIC MACROCYCLES CONTAINING A 1,3-BIS(1H-PYRAZOL-1-YL)PROPANE UNIT

Authors
CONDE S FIERROS M DORRONSORO I JIMENO ML RODRIGUEZFRANCO MI
Citation
S. Conde et al., REGIOSELECTIVE LIPASE-CATALYZED SYNTHESIS OF DIESTER CROWNS - NEW ASYMMETRIC MACROCYCLES CONTAINING A 1,3-BIS(1H-PYRAZOL-1-YL)PROPANE UNIT, Tetrahedron, 53(33), 1997, pp. 11481-11488
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
33
Year of publication
1997
Pages
11481 - 11488
Database
ISI
SICI code
0040-4020(1997)53:33<11481:RLSODC>2.0.ZU;2-#
Abstract
Regioselective lipase catalyzed intramolecular transesterification of dipyrazolic tetraester 1 with di-, tri- and tetraethyleneglycol afford ed symmetric and, in smaller amounts, asymmetric diester crowns includ ing a 1,3-bis(1H-pyrazol-1-yl)propane unit. Their structures have been unequivocally elucidated after their H-1 and C-13 NMR spectra and WEP T experiments. (C) 1997 Elsevier Science Ltd.