Ck. Wang et Jyy. Lee, MONOSYMPTOMATIC HYPOCHONDRIACAL PSYCHOSIS COMPLICATED BY SELF-INFLICTED SKIN ULCERATION, SKULL DEFECT AND BRAIN-ABSCESS, British journal of dermatology, 137(2), 1997, pp. 299-302
Self-inflicted dermatoses are associated with personality disorders an
d psychoses, including monosymptomatic hypochondriacal psychosis (MHP)
, which is characterized by a delusion involving a particular hypochon
driacal concern, We report an unusual case of MHP with severe mutilati
on of the skin complicated by a skull defect and brain abscess. The pa
tient was a 66-year-old uneducated man who damaged his forehead repeat
edly because he believed that a 'toxic root' in the forehead was the s
ource of his general ailment, He admitted that the lesions were self-i
nflicted. There was no other evidence of psychosis or primary skin dis
ease and MHP was diagnosed, Despite initial favourable response to pim
ozide, the patient was lost to follow-up for 4 years, during which he
continued to damage his forehead and applied corrosive agents, He was
then referred with a personality change and a 6 x 4 cm bony defect in
the skull, complicated by herniation and abscess of the left frontal l
obe, This case represents one of the most severe examples of self-muti
lation ever reported. The differential diagnosis of dermatitis artefac
ta and the principles of treating MHP are discussed.