Je. Parker et Mj. Coleman, MOLECULAR INTIMACY BETWEEN PROTEINS SPECIFYING PLANT-PATHOGEN RECOGNITION, Trends in biochemical sciences, 22(8), 1997, pp. 291-296
Disease resistance in plants is commonly specified by genetically pair
ed plant resistance (R) and pathogen avirulence (Avr) proteins. Recent
molecular analyses of several R-Avr protein interactions provide comp
elling evidence for a receptor-ligand mechanism in which specific bind
ing of the Avr elicitor by its matching R protein leads to activation
of the plant defence response. Direct R-Avr protein recognition preced
es the function of an expanding battery of plant resistance signalling
components.