Background: The report presented is an update on continuing developmen
t work on modified PHEMA core-and-shirt KPros in animals. Methods: Two
variations (improved wet-eye, and dry-eye) of a prototype core-and-sk
irt Chirila KPro are described. The clinical success rate on implantat
ion of these versions of the Chirila KPro was assessed. Results: It wa
s found that a significant improvement in retention rate was shown in
the improved model but. that the dry-eye model failed early in two of
the three implanted. Conclusions: The significance of the improved str
ength and the reasons for disappointing results with the early dry-eye
KPros are discussed. Ongoing work is briefly outlined.