38-CHLORINE ABSORPTION IN PATIENTS WITH M AINZ POUCH-I

The object of this study was to investigate the effect of the time fac tor on radioactive chlorine absorption in patients with a continent il eocecal reservoir (Mainz pouch I). The study was conducted on 20 patie nts who had undergone a Mainz pouch I urinary diversion (15 males and 5 females). The mean age was 47 (15-72) years. 20 MBq of radioactive 3 8-chlorine was instilled into the pouch. Radioactivity was determined in the blood, pouch and the body interstitium ever 20 minutes for 3 ho urs. Samples for arterial blood gas and acid-base profile were obtaine d before and after instillation. The investigated patients were divide d into 3 groups according to the length of postoperative follow up: gr oup 1, less than 7 months (n=7), group 2, between 7 and 12 months (n=8 ) and group 3, more than 12 months (n=5). The results showed that 92.8 % of the instilled chlorine was absorbed into the circulation in patie nts of group 1, while 51.2% was absorbed in patients of group 3. Resul ts of the acid profile showed no significant changes before or after 3 8-chlorine instillation. The study provided evidence for marked reduct ion of chlorine absorption over the course of time in patients with Ma inz pouch I.