Childhood hydronephrosis (HN) is accurately detected by ultrasound (US
), but its functional work-up remains a domain of scintigraphy, the Wh
itaker-test. and clinical follow-up. We utilized color doppler US (CD-
Jet) of uretero-vesical jets (UVJ) to visualize the postobstructive ur
eteral flow in childhood HN. A total of 177 standardized CD-Jet were p
erformed in 132 children aged 1 day to 14.9 years. Sixty-nine investig
ations in 43 patients with unilateral HN were compared with a standard
ized technetium 99m-mercaptotriacetylglycine nephrogram: in 10 infants
both procedures were performed consecutively on the same day. UVJ wer
e visible in 96% of all investigations. Ureteral obstruction resulted
in absence of UVJ in 85% of examinations: in the remaining 15% the jet
frequency was less than 10% observed in the contralateral control. Re
sults are highly significant in both uretero-pelvic (P<0.00007) and ur
etero-vesical lesions (P<0.00005, Wilcoxon test) and are reproducible
in sequential investigations. In nonobstructive distal HN the jet freq
uency averaged 70% of the unaffected side (P<0.05). In proximal lesion
s it is equal. Jet evaluation in reflux nephropathy did not differ fro
m controls. Compared with scintigraphy. CD-US identifies obstruction w
ith a specificity of 94.2% and sensitivity of 94.8%. CD-US of UVJ ther
efore may serve as a reliable screening parameter in unilateral childh
ood HN.