A man with shoulder pain, wasting, and weakness had ipsilateral crania
l nerve abnormalities. Electrodiagnostic studies supported a diagnosis
of neuralgic amyotrophy, but we later demonstrated a spinal accessory
mononeuropathy with ipsilateral hypoglossal weakness (Collet-Sicard s
yndrome). Magnetic resonance imaging demonstrated an inaccessible occi
pital condyle mass, and disseminated adenocarcinoma was subsequently d
iagnosed. Although cranial mononeuropathies can occur in neuralgic amy
otrophy, this case illustrates the importance of identifying a focal l
esion, and highlights the localizing value of electrodiagnosis. (C) 19
97 John Wiley & Sons, Inc.