AUTOSOMAL-DOMINANT CENTRONUCLEAR MYOPATHY - REPORT OF A NEW FAMILY WITH CLINICAL-FEATURES SIMULATING FACIOSCAPULOHUMERAL SYNDROME

The centronuclear myopathies are a clinically and genetically heteroge neous group of disorders which share similar histological features on muscle biopsy. The familiar cases have been classified genetically as X-linked or autosomal in inheritance. The autosomal forms usually have a later onset and milder course as compared to the X-linked form. Thi rteen families with autosomal dominant centronuclear myopathy have bee n previously described. We describe an additional family with unique c linical features which initially suggested a facioscapulohumeral syndr ome. (C) 1997 John Wiley & Sons, Inc.