PHYSICAL OR TEMPORAL SEPARATION OF OLESTRA AND VITAMIN-A, VITAMIN-E AND VITAMIN-D INTAKE DECREASES THE EFFECT OF OLESTRA ON THE STATUS OF THE VITAMINS IN THE PIG

A study was conducted in the domestic pig to determine 1) whether feed ing olestra mixed in the diet exaggerated olestra effects on fat-solub le vitamin status compared with the effects of feeding it in a typical snack food, and 2) whether separating olestra consumption temporally from vitamin consumption affected the influence of olestra on vitamin status, Groups of 10 pigs each, five castrated males and five females, were fed 2.2% (wt/wt) olestra for 4 wk in purified diet that provided 1 time the National Research Council's requirements for swine of all micronutrients. The olestra was either mixed in the purified diet or f ed in potato chips, The potato chips were given to the pigs at all thr ee feedings, at the noon feeding only, or between the noon and the eve ning feedings, A control group was fed the purified diet with no olest ra. The effects of olestra on indices of vitamin A, D and E status wer e from 1.7 to 4.5 times greater when olestra was fed three times daily mixed in the diet than when it was fed three limes daily in potato ch ips, Because the effect of olestra on the status of the fat-soluble vi tamins was diminished substantially by feeding the olestra in potato c hips, it was not possible to conclude definitively how the temporal se paration of olestra and vitamin consumption affected the olestra effec t on vitamin status.